Reticulum cell sarcoma pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

The dominant cell type is thought to be derived from histiocytes or macrophages. More recent thinking indicates that this cancer may arise from lymphocytes or immunoblasts.

• Large, foam filled histiocytes with numerous mitoses and scant stroma are present
• Stains for reticulum are positive
• Periodic Acid Schiff (PAS) stains are negative

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