SMILE regimen
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]
Overview
SMILE regimen refers to a regimen consisting of Steroid (Dexamethasone), Methotrexate, Ifosfamide, L-asparaginase, Etoposide used to treat NK/T-cell lymphoma[1]
Regimen
SSteroid (Dexamethasone)
MMethotrexate
IIfosfamide
LL-asparaginase
EEtoposide
Indications
References
- ↑ 1.0 1.1 Yamaguchi M, Suzuki R, Kwong YL, Kim WS, Hasegawa Y, Izutsu K; et al. (2008). “Phase I study of dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide (SMILE) chemotherapy for advanced-stage, relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma and leukemia”. Cancer Sci. 99 (5): 1016–20. doi:10.1111/j.1349-7006.2008.00768.x. PMID 18294294.
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH