Sarcomatoid carcinoma of the lung diagnostic study of choice
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]
Overview
The diagnostic modality of choice for sarcomatoid carcinoma of the lung is CT scan of the chest. The definitive diagnosis of sarcomatoid carcinoma of the lung is made by biopsy of the tumor.
Diagnostic Study of Choice
- Diagnostic modality of choice for sarcomatoid carcinoma of lung is CT scan of the chest.[1]
- The definitive diagnosis of sarcomatoid carcinoma of the lung is made by immunohistochemical analysis and pathological subtyping of the specimen collected from biopsy, needle aspiration, sputum cytology or surgical resection of the tumor.[2]
- The algorithm below summarizes the initial imaging approach for patients with suspected non-small cell lung cancer.[3][4]
Suspected lung cancer | |||||||||||||||||||||||||||||||
| Chest X-Ray | |||||||||||||||||||||||||||||||
| Abnormal | Normal | ||||||||||||||||||||||||||||||
Enhanced Computed Tomography (ECT), includes: • Thorax • Upper Abdomen • Low Neck | Manage and observe | ||||||||||||||||||||||||||||||
Imaging evaluation | |||||||||||||||||||||||||||||||
Location • Central • Peripheral • Pleural lesion Size Lesion characteristics • Margins (irregular/regular) • Shape (spiculated/rounded) Presence of cavitation • Yes • No Type of adenopathy • Hiliar • Mediastinal | |||||||||||||||||||||||||||||||
Other Imaging or Diagnostic Modalities • Sputum cytology • Endobronchial ultrasound • Endoscopic ultrasound • Bronchoscopy • Mediastinoscopy • PET/CT | |||||||||||||||||||||||||||||||
References
- ↑ Purandare, NilenduC; Rangarajan, Venkatesh (2015). “Imaging of lung cancer: Implications on staging and management”. Indian Journal of Radiology and Imaging. 25 (2): 109. doi:10.4103/0971-3026.155831. ISSN 0971-3026.
- ↑ Roesel, Christian; Terjung, Sarah; Weinreich, Gerhard; Hager, Thomas; Chalvatzoulis, Eleftherios; Metzenmacher, Martin; Welter, Stefan (2016). “Sarcomatoid carcinoma of the lung: a rare histological subtype of non-small cell lung cancer with a poor prognosis even at earlier tumour stages”. Interactive CardioVascular and Thoracic Surgery: ivw392. doi:10.1093/icvts/ivw392. ISSN 1569-9293.
- ↑ Non-small cell lung cancer: Adenocarcinoma of the lung. Radiopedia.http://radiopaedia.org/articles/adenocarcinoma-of-the-lung Accessed on March 1, 2016
- ↑ WHO: Lung cancer/Tumours of the Lung. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-chap1.pdf Accessed on March 1, 2016
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