Sarcomatoid carcinoma of the lung historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Overview

Sarcomatoid carcinoma is a rare type of malignant tumor. The name sarcomatoid carcinoma was first described by Virchow in 1865 as a “biphasic” lesion of adenocarcinomatous or squamous cell carcinoma with spindle cell or giant cell component.

Historical Perspective

Sarcomatoid carcinoma is a rare type of malignant tumor. The name sarcomatoid carcinoma was first described by Virchow in 1865 as a “biphasic” lesion of adenocarcinomatous or squamous cell carcinoma with spindle cell or giant cell component.

Discovery

Sarcomatoid carcinoma was first described by Virchow in 1865 as a “biphasic” lesion of adenocarcinomatous or squamous cell carcinoma with spindle cell or giant cell component.^[1]
In 1981, World Health Organization (WHO) classification on lung cancers, mentioned pleomorphic carcinomas showing a prevalence of spindle or giant cells as morphologic variants of squamous cell carcinomas and large-cell carcinomas, respectively, and defined carcinosarcomas as biphasic tumors consisting of an intimate admixture of carcinoma and sarcoma.^[2]

References

↑ Virchow, Rudolf (1863). Die KRANKHAFTEN GESCHWÜLSTE. 2. Retrieved 1864. Check date values in: |access-date= (help)
↑ Sobin LH (1981). “The international histological classification of tumours”. Bull. World Health Organ. 59 (6): 813–9. PMC 2396133. PMID 6978190.

Template:WH Template:WS Template:Tumors

[1] Virchow, Rudolf (1863). Die KRANKHAFTEN GESCHWÜLSTE. 2. Retrieved 1864. Check date values in: |access-date= (help)

[pmid6978190-2] Sobin LH (1981). “The international histological classification of tumours”. Bull. World Health Organ. 59 (6): 813–9. PMC 2396133. PMID 6978190.

[1]

[2]