Schwannoma medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]

Overview

Medical therapy

There is no obvious medical treatment for schwannomas other than managing the symptoms.

Radiotherapy

Stereotactic radiosurgery (SRS) ^[1]^[2]^[3]
Fractionated stereotactic radiotherapy (FSRT)

SRS is the most commonly used between these as it causes minimal injury to adjacent tissues. However, there is a risk of progressive hearing deterioration associated with radiotherapy for vestibular schwannomas.

References

↑ Lin EP, Crane BT (November 2017). “The Management and Imaging of Vestibular Schwannomas”. AJNR Am J Neuroradiol. 38 (11): 2034–2043. doi:10.3174/ajnr.A5213. PMC 5690865. PMID 28546250.
↑ Persson O, Bartek J, Shalom NB, Wangerid T, Jakola AS, Förander P (June 2017). “Stereotactic radiosurgery vs. fractionated radiotherapy for tumor control in vestibular schwannoma patients: a systematic review”. Acta Neurochir (Wien). 159 (6): 1013–1021. doi:10.1007/s00701-017-3164-6. PMC 5425507. PMID 28409393.
↑ Mulder JJ, Kaanders JH, van Overbeeke JJ, Cremers CW (October 2012). “Radiation therapy for vestibular schwannomas”. Curr Opin Otolaryngol Head Neck Surg. 20 (5): 367–71. doi:10.1097/MOO.0b013e328357d337. PMID 22931906.

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[pmid28546250-1] Lin EP, Crane BT (November 2017). “The Management and Imaging of Vestibular Schwannomas”. AJNR Am J Neuroradiol. 38 (11): 2034–2043. doi:10.3174/ajnr.A5213. PMC 5690865. PMID 28546250.

[pmid28409393-2] Persson O, Bartek J, Shalom NB, Wangerid T, Jakola AS, Förander P (June 2017). “Stereotactic radiosurgery vs. fractionated radiotherapy for tumor control in vestibular schwannoma patients: a systematic review”. Acta Neurochir (Wien). 159 (6): 1013–1021. doi:10.1007/s00701-017-3164-6. PMC 5425507. PMID 28409393.

[pmid22931906-3] Mulder JJ, Kaanders JH, van Overbeeke JJ, Cremers CW (October 2012). “Radiation therapy for vestibular schwannomas”. Curr Opin Otolaryngol Head Neck Surg. 20 (5): 367–71. doi:10.1097/MOO.0b013e328357d337. PMID 22931906.

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