Scombrotoxic fish poisoning medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Treatment is generally unnecessary, but antihistamines or epinephrine may be needed in certain instances.

Treatment is in the form of supportive care such as fluids and oxygen. H1 and H2 receptor (histamine receptors) blocking medications can also be given with some success. Oral anti-histamines are very effective, showing improvement within 10–15 minutes.

http://www.cdc.gov/ncidod/dbmd/diseaseinfo/marinetoxins_g.htm