Scombrotoxic fish poisoning pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Scombrotoxic fish poisoning is caused by bacterial spoilage of certain finfish such as tuna, mackerel, bonito, and, rarely, other fish. As bacteria break down fish proteins, byproducts such as histamine and other substances that block histamine breakdown build up in fish.

http://www.cdc.gov/ncidod/dbmd/diseaseinfo/marinetoxins_g.htm