Secondary amyloidosis laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Shaghayegh Habibi, M.D.[3]
Overview
An elevated urinary protein is suggestive of secondary amyloidosis. Elevated level of acute phase reactant, abnormal liver function test, and other findings may also be observed.
Laboratory Findings
- Laboratory findings suggestive of secondary amyloidosis vary depending on the affected organ.[1]
- The most commonly observable finding is proteinuria, particularly nephrotic range (>3.5 g/day).
- Other possible laboratory findings include:[2]
- Elevated NT-proBNP in case of cardiac involvement.
- Alkaline phosphatase Value >1.5 upper limit of normal in case of liver involvement.
- Elevated level of acute phase reactant due to underlying inflammatory condition.
References
- ↑ Papa, Riccardo; Lachmann, Helen J. (2018). “Secondary, AA, Amyloidosis”. Rheumatic Disease Clinics of North America. 44 (4): 585–603. doi:10.1016/j.rdc.2018.06.004. ISSN 0889-857X.
- ↑ Real de Asua, Diego; Galvan, Jose Maria; Filigghedu, Maria Teresa; Trujillo, Davinia; Costa, Ramon; Cadinanos, Julen (2014). “Systemic AA amyloidosis: epidemiology, diagnosis, and management”. Clinical Epidemiology: 369. doi:10.2147/CLEP.S39981. ISSN 1179-1349.
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH