Seminoma classification
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
Based on the histology, testicular seminoma may be classified into three subtypes: classic, anaplastic, and spermatocytic.[1]
Classification
Based on the histology, testicular seminoma may be classified into three subtypes:[1][2]
- Classic: 85%, infrequent mitoses, monotonous sheet of large cells with abundant cytoplasm and round hyperchromatic nuclei, prominent nucleoli
- Anaplastic: 10%, 3 or more mitotic figures per high-power field
- Spermatocytic: 5%, older male patients above 60 years old, rarely metastasise; well-differentiated with cells resembling secondary spermatids
References
- ↑ 1.0 1.1 Pathology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ Boujelbene N, Cosinschi A, Boujelbene N, Khanfir K, Bhagwati S, Herrmann E, Mirimanoff RO, Ozsahin M, Zouhair A (August 2011). “Pure seminoma: a review and update”. Radiat Oncol. 6: 90. doi:10.1186/1748-717X-6-90. PMID 21819630.
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