Sickle-cell disease surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2]

Overview

Surgical intervention is generally not recommended for the management of sickle-cell disease. However, certain surgeries may be performed for specific complications.

Surgery

The mainstay of treatment for sickle cell disease is medical therapy. Surgery is usually reserved for patients with either:^[1]^[2]

First episode of a splenic sequestration crisis
Cholecystitis or symptoms of gallbladder disease
Choledocholithiasis

References

↑ Ballas SK, Kesen MR, Goldberg MF, Lutty GA, Dampier C, Osunkwo I; et al. (2012). “Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management”. ScientificWorldJournal. 2012: 949535. doi:10.1100/2012/949535. PMC 3415156. PMID 22924029.
↑ Buck J, Davies SC (October 2005). “Surgery in sickle cell disease”. Hematol. Oncol. Clin. North Am. 19 (5): 897–902, vii. doi:10.1016/j.hoc.2005.07.004. PMID 16214650.

[pmid22924029-1] Ballas SK, Kesen MR, Goldberg MF, Lutty GA, Dampier C, Osunkwo I; et al. (2012). “Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management”. ScientificWorldJournal. 2012: 949535. doi:10.1100/2012/949535. PMC 3415156. PMID 22924029.

[pmid16214650-2] Buck J, Davies SC (October 2005). “Surgery in sickle cell disease”. Hematol. Oncol. Clin. North Am. 19 (5): 897–902, vii. doi:10.1016/j.hoc.2005.07.004. PMID 16214650.

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