Sideroblastic anemia surgery
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.
Overview
In severe cases, bone marrow transplant is the only option with limited information about the success rate.
Surgery
Indications
- Surgery is not the first-line treatment option for patients with sideroblastic anemia.[1]
- The indications for surgery are:
- Young patients with congenital sideroblastic anemia, not responsive to pyridoxine
- Transfusion dependent patients
- Liver cirrhosis
- Iron overload refractory to iron chelation therapy
- Iron overload refractory to phlebotomy
Contraindications
- Patients with organ damage from secondary hemochromatosis
- Poor surgical candidacy
References
- ↑ Rouault TA (June 2016). “Mitochondrial iron overload: causes and consequences”. Curr. Opin. Genet. Dev. 38: 31–37. doi:10.1016/j.gde.2016.02.004. PMC 5035716. PMID 27026139.
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