Silent thyroiditis epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S [2]

Overview

Silent thyroiditis is a rare disease with the incidence of up to 23000 per 100,000 individuals with hyperthyroidism. The prevalence of silent thyroiditis is approximately 1000 per 100,000 individuals with thyrotoxicosis. Silent thyroiditis commonly affects patients in 30-40 years of age. Females are more commonly affected by silent thyroiditis than males. The female to male ratio is approximately 4 to 1. Silent thyroiditis is more common in areas of higher dietary iodine intake.

Epidemiology and Demographics

Incidence

The incidence of silent thyroiditis is up to 23000 per 100,000 individuals with hyperthyroidism.^[1]^[2]

Prevalence

The prevalence of silent thyroiditis is approximately 1000 per 100,000 individuals with thyrotoxicosis.^[3]^[4]

Age

Silent thyroiditis commonly affects patients in 30-40 years of age.^[5]

Race

There is no racial predilection to silent thyroiditis.

Gender

Females are more commonly affected by silent thyroiditis than males. The female to male ratio is approximately 4 to 1.^[4]

Region

Silent thyroiditis is more common in areas of higher dietary iodine intake. It is more common in the great lakes area of North America and Japan.^[5]^[6]

References

↑ Nikolai TF, Brosseau J, Kettrick MA, Roberts R, Beltaos E (1980). “Lymphocytic thyroiditis with spontaneously resolving hyperthyroidism (silent thyroiditis)”. Arch. Intern. Med. 140 (4): 478–82. PMID 6892676.
↑ Schorr AB, Miller JL, Shtasel P, Rose LI (1986). “Low incidence of painless thyroiditis in the Philadelphia area”. Clin Nucl Med. 11 (6): 379–80. PMID 3720149.
↑ Ross DS (1998). “Syndromes of thyrotoxicosis with low radioactive iodine uptake”. Endocrinol. Metab. Clin. North Am. 27 (1): 169–85. PMID 9534035.
↑ ^4.0 ^4.1 Pearce EN, Farwell AP, Braverman LE (2003). “Thyroiditis”. N. Engl. J. Med. 348 (26): 2646–55. doi:10.1056/NEJMra021194. PMID 12826640.
↑ ^5.0 ^5.1 Samuels MH (2012). “Subacute, silent, and postpartum thyroiditis”. Med. Clin. North Am. 96 (2): 223–33. doi:10.1016/j.mcna.2012.01.003. PMID 22443972.
↑ Vitug AC, Goldman JM (1985). “Silent (painless) thyroiditis. Evidence of a geographic variation in frequency”. Arch. Intern. Med. 145 (3): 473–5. PMID 3838433.

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[pmid6892676-1] Nikolai TF, Brosseau J, Kettrick MA, Roberts R, Beltaos E (1980). “Lymphocytic thyroiditis with spontaneously resolving hyperthyroidism (silent thyroiditis)”. Arch. Intern. Med. 140 (4): 478–82. PMID 6892676.

[pmid3720149-2] Schorr AB, Miller JL, Shtasel P, Rose LI (1986). “Low incidence of painless thyroiditis in the Philadelphia area”. Clin Nucl Med. 11 (6): 379–80. PMID 3720149.

[pmid9534035-3] Ross DS (1998). “Syndromes of thyrotoxicosis with low radioactive iodine uptake”. Endocrinol. Metab. Clin. North Am. 27 (1): 169–85. PMID 9534035.

[pmid12826640-4] 4.0 ^4.1 Pearce EN, Farwell AP, Braverman LE (2003). “Thyroiditis”. N. Engl. J. Med. 348 (26): 2646–55. doi:10.1056/NEJMra021194. PMID 12826640.

[pmid22443972-5] 5.0 ^5.1 Samuels MH (2012). “Subacute, silent, and postpartum thyroiditis”. Med. Clin. North Am. 96 (2): 223–33. doi:10.1016/j.mcna.2012.01.003. PMID 22443972.

[pmid3838433-6] Vitug AC, Goldman JM (1985). “Silent (painless) thyroiditis. Evidence of a geographic variation in frequency”. Arch. Intern. Med. 145 (3): 473–5. PMID 3838433.

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