Sjögren's syndrome historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
In 1892, Johann von Mikulicz-Radecki was to first to describe a patient with with enlargement of the parotid and lacrimal glands associated with a round-cell infiltrate and acinar atrophy. In 1933, Henrik Sjögren was the first to describe 19 females with clinical and pathological manifestations of the Sjögren’s syndrome.
Historical Perspective
Discovery
- In 1892, Johann von Mikulicz-Radecki was to first to describe a patient with enlargement of the parotid and lacrimal glands associated with a round-cell infiltrate and acinar atrophy.[1]
- In 1933, Henrik Sjögren was the first to describe 19 females with clinical and pathological manifestations of the Sjögren’s syndrome.
- In 1951, Sjögren published a paper describing 80 patients with keratoconjunctivitis sicca associated with Sjögren’s syndrome.
- In 1976, the first symposium on Sjogren’s syndrome was held in Sweden.[2]
- In 1980, autoantibodies to the centromere proteins (CENP) were found in 40% of patients with Sjögren’s syndrome.[3]
References
- ↑ Talal N (August 1992). “Sjögren’s syndrome: historical overview and clinical spectrum of disease”. Rheum. Dis. Clin. North Am. 18 (3): 507–15. PMID 1496158.
- ↑ Bjelle, A. (1987). “Historical Perspective: The Early Years (1930–1960)”: 3–6. doi:10.1007/978-3-642-50118-0_1.
- ↑ Fritzler, Marvin J.; Rattner, Jerome B.; Luft, LeeAnne M.; Edworthy, Steven M.; Casiano, Carlos A.; Peebles, Carol; Mahler, Michael (2011). “Historical perspectives on the discovery and elucidation of autoantibodies to centromere proteins (CENP) and the emerging importance of antibodies to CENP-F”. Autoimmunity Reviews. 10 (4): 194–200. doi:10.1016/j.autrev.2010.09.025. ISSN 1568-9972.
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