Small intestine cancer surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Parminder Dhingra, M.D. [3]

Overview

Curative surgery is the primary modality for treating small intestine cancers, in combination with chemotherapy and radiotherapy.

Primary treatment for cancer of the small intestine is curative surgical resection.^[1]^[2]

For non-metastatic disease curative surgery gives good results, when done in a tertiary care center.^[3]
Adenocarcinoma of duodenum has a comparative low 5-year disease free survival rate after surgery.^[3]
Although surgical resection of small intestinal cancer plays an important role in the treatment, 5 yr survival rate is low even after surgery.^[4]
Small intestine resection: In this operation, surgeon removes the piece of intestine that has the tumor and some of the normal tissue on each side of the tumor.
Palliative operation: If small intestine cancer has spread too far in the abdomen, the surgeon will do a palliative operation.
The goal of palliative resection is to decrease symptoms such as abdominal pain and abdominal distension.
For tumors of jejunum and ileum and wide local excision to remove the tumor may be done.^[5]
For duodenal cancer Whipple’s procedure may be done.

↑ Higashi D, Ishibashi Y, Tamura T, Nii K, Egawa Y, Koga M, Tomiyasu T, Harimura T, Tanaka R, Futatsuki R, Noda S, Futami K, Maekawa T, Takaki Y, Hirai F, Matsui T (August 2010). “Clinical features of and chemotherapy for cancer of the small intestine”. Anticancer Res. 30 (8): 3193–7. PMID 20871040.
↑ Talamonti MS, Goetz LH, Rao S, Joehl RJ (May 2002). “Primary cancers of the small bowel: analysis of prognostic factors and results of surgical management”. Arch Surg. 137 (5): 564–70, discussion 570–1. PMID 11982470.
↑ ^3.0 ^3.1 Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J (August 2004). “Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients”. Cancer. 101 (3): 518–26. doi:10.1002/cncr.20404. PMID 15274064.
↑ Coco C, Rizzo G, Manno A, Mattana C, Verbo A (April 2010). “Surgical treatment of small bowel neoplasms”. Eur Rev Med Pharmacol Sci. 14 (4): 327–33. PMID 20496543.
↑ ^5.0 ^5.1 “Adenocarcinoma of the small bowel – Surgical Treatment – NCBI Bookshelf”.