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Stevens-Johnson syndrome other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anila Hussain, MD [2]

Overview

Some people have a genetic predisposition which increases their risk of developing SJS in response to certain trigger medications. Genetic testing can be done to identify genetic predisposition in those with a family history or recurrent episodes of SJS

Other Diagnostic Studies

Some people have a genetic predisposition which increases their risk of developing SJS in response to certain trigger medications. Genetic testing can be done to identify genetic predisposition in those with a family history or recurrent episodes of SJS[1][2][3]

References

  1. Li X, Yu K, Mei S, Huo J, Wang J, Zhu Y; et al. (2015). “HLA-B*1502 increases the risk of phenytoin or lamotrigine induced Stevens-Johnson Syndrome/toxic epidermal necrolysis: evidence from a meta-analysis of nine case-control studies”. Drug Res (Stuttg). 65 (2): 107–11. doi:10.1055/s-0034-1375684. PMID 24871931. Check |pmid= value (help).
  2. “[Abstracts of the 23d meeting of the Clinical Immunology Working Group of the East German Society of Clinical and Experimental Immunology organized jointly with the 16th meeting of the Working Group on Infection Immunology of the East German Society of Microbiology and Epidemiology. Berlin, 14 May 1987]”. Allerg Immunol (Leipz). 34 (2): 119–33. 1988. PMID 3189112  Check |pmid= value (help).
  3. McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperavičiūtė D, Carrington M; et al. (2011). “HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans”. N Engl J Med. 364 (12): 1134–43. doi:10.1056/NEJMoa1013297. PMC 3113609. PMID 21428769.

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