Subdural empyema epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]; Anthony Gallo, B.S. [3]

Overview

Subdural empyema accounts for approximately 15-25% of focal central nervous system infections. In 2014, the incidence of subdural empyema was estimated to be less than 1 case per 100,000 individuals.^[1] Prior to antibiotics, the case fatality rate of subdural empyema was estimated to be near 100%. However, with antibiotics, the current rate is estimated between 10-20%.^[2] The disease usually occurs in children and young adults (70% cases occurring in the second and third decades of life), being more frequent in men than women, possibly due to sex-related differences in sinus anatomy.

Epidemiology and Demographics

Incidence

In 2014, the incidence of subdural empyema was estimated to be less than 1 case per 100,000 individuals.^[1]

Case Fatality Rate

Prior to antibiotics, the case fatality rate of subdural empyema was estimated to be near 100%. However, with antibiotics, the current rate is estimated between 10-20%.^[2]

Age

Subdural empyema may affect patients of any age group.^[1] Subdural empyema most commonly affects individuals younger than 20 years of age, as approximately 70% of cases occur in the second and third decades of life.^[3]

Gender

Males are more commonly affected with subdural empyema name than females. The male to female ratio is approximately 6 to 1.^[2]

Race

There is no racial predilection to subdural empyema.

References

↑ ^1.0 ^1.1 ^1.2 French H, Schaefer N (2014). “Intracranial Subdural Empyema: A 10-Year Case Series”. Oschner J. 12 (2). doi:10.1002/bip.360240911. PMID PMC4052585 Check |pmid= value (help).
↑ ^2.0 ^2.1 ^2.2 Nathoo N, Nadvi SS, van Dellen JR, Gouws E (1999). “Intracranial subdural empyemas in the era of computed tomography: a review of 699 cases”. Neurosurgery. 44 (3): 529–35, discussion 535–6. PMID 10069590.
↑ Wu TJ, Chiu NC, Huang FY (2008). “Subdural empyema in center”. J Microbiol Immunol Infect. 41 (1): 62–7. PMID 18327428. Unknown parameter |month= ignored (help)

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[PMC4052585-1] 1.0 ^1.1 ^1.2 French H, Schaefer N (2014). “Intracranial Subdural Empyema: A 10-Year Case Series”. Oschner J. 12 (2). doi:10.1002/bip.360240911. PMID PMC4052585 Check |pmid= value (help).

[pmid10069590-2] 2.0 ^2.1 ^2.2 Nathoo N, Nadvi SS, van Dellen JR, Gouws E (1999). “Intracranial subdural empyemas in the era of computed tomography: a review of 699 cases”. Neurosurgery. 44 (3): 529–35, discussion 535–6. PMID 10069590.

[pmid18327428-3] Wu TJ, Chiu NC, Huang FY (2008). “Subdural empyema in center”. J Microbiol Immunol Infect. 41 (1): 62–7. PMID 18327428. Unknown parameter |month= ignored (help)

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