Subependymal giant cell astrocytoma CT

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2], Sujit Routray, M.D. [3]

Overview

On head CT, some of the findings that are suggestive of subependymal giant cell astrocytoma include a heterogenous mass with uniform post contrast enhancement, enlargement of the ventricles, and iso- or slightly hypoattenuating to grey matter.

CT

Head CT scan may be helpful in the diagnosis of subependymal giant cell astrocytoma. Findings on CT scan suggestive of/diagnostic of subependymal giant cell astrocytoma include:^[1]^[2]^[3]^[4]

Round, heterogeneous mass
Uniform post-contrast enhancement
Cyst
Calcification
Iso- or slightly hypoattenuating to grey matter
Enlargement of the ventricles
Perilesional edema

Axial brain CT scan showing an intraventricular mass in the right foramen of Monro area, with cystic and solid components and small areas of calcification. There is a contrast enhancement of solid component. Also multiple calcified subependymal nodules are seen source:Case courtesy of Dr Ilkhom Nalibaev, <a href=”https://radiopaedia.org/”>Radiopaedia.org</a>. From the case <a href=”https://radiopaedia.org/cases/48054″>rID: 48054</a>

References

↑ Jung TY, Kim YH, Jung S, Baek HJ, Lee KH (2015). “The clinical characteristics of subependymal giant cell astrocytoma: five cases”. Brain Tumor Res Treat. 3 (1): 44–7. doi:10.14791/btrt.2015.3.1.44. PMC 4426277. PMID 25977907.
↑ Stein JR, Reidman DA (2016). “Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis”. Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.
↑ Moran V, O’Keeffe F (1986). “Giant cell astrocytoma in tuberous sclerosis: computed tomographic findings”. Clin Radiol. 37 (6): 543–5. doi:10.1016/s0009-9260(86)80009-5. PMID 3791849.
↑ Beaumont, Thomas L.; Godzik, Jakub; Dahiya, Sonika; Smyth, Matthew D. (2015). “Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report”. Journal of Neurosurgery: Pediatrics. 16 (2): 134–137. doi:10.3171/2015.1.PEDS13146. ISSN 1933-0707.

Template:WikiDoc Sources

[pmid25977907-1] Jung TY, Kim YH, Jung S, Baek HJ, Lee KH (2015). “The clinical characteristics of subependymal giant cell astrocytoma: five cases”. Brain Tumor Res Treat. 3 (1): 44–7. doi:10.14791/btrt.2015.3.1.44. PMC 4426277. PMID 25977907.

[pmid26942030-2] Stein JR, Reidman DA (2016). “Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis”. Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.

[pmid3791849-3] Moran V, O’Keeffe F (1986). “Giant cell astrocytoma in tuberous sclerosis: computed tomographic findings”. Clin Radiol. 37 (6): 543–5. doi:10.1016/s0009-9260(86)80009-5. PMID 3791849.

[BeaumontGodzik2015-4] Beaumont, Thomas L.; Godzik, Jakub; Dahiya, Sonika; Smyth, Matthew D. (2015). “Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report”. Journal of Neurosurgery: Pediatrics. 16 (2): 134–137. doi:10.3171/2015.1.PEDS13146. ISSN 1933-0707.

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