Syndrome of inappropriate antidiuretic hormone history and symptoms
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Symptoms of SIADH depend on the level of sodium in the blood and the rate at which the level of sodium falls. Symptoms may be non-specific, such as generalized fatigue and weakness; but in case of severe disease, symptoms, such as irritability, nausea, vomiting, muscle weakness and cramps, loss of appetite, confusion, personality changes, hallucinations, seizures, stupor, and coma may be seen.
History and Symptoms
- Symptoms vary depending on the severity of hyponatremia and the rate at which serum sodium concentration falls.
- Symptoms of SIADH include:[1]
- Nausea and vomiting
- Loss of appetite
- Fatigue and weakness
- Irritability
- Personality changes, such as combativeness
- Seizures
- Confusion
- Hallucinations
- Stupor
- Coma
References
- ↑ Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, Decaux G, Fenske W, Hoorn EJ, Ichai C, Joannidis M, Soupart A, Zietse R, Haller M, van der Veer S, van Biesen W, Nagler E, Gonzalez-Espinoza L, Ortiz A (2017). “Hyponatraemia diagnosis and treatment clinical practice guidelines”. Nefrologia. 37 (4): 370–380. doi:10.1016/j.nefro.2017.03.021. PMID 28619670.
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