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TAX1BP1

Tax1-binding protein 1 is a protein that in humans is encoded by the TAX1BP1 gene.[1]


Interactions

TAX1BP1 has been shown to interact with TNFAIP3[2] and TRAF6.[3] TAX1BP1 binds to TNFAIP3 or TRAF6 and suppresses NF-kappaB transcriptional activation.

References

  1. “Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1”.
  2. De Valck, D; Jin D Y; Heyninck K; Van de Craen M; Contreras R; Fiers W; Jeang K T; Beyaert R (July 1999). “The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases”. Oncogene. ENGLAND. 18 (29): 4182–90. doi:10.1038/sj.onc.1202787. ISSN 0950-9232. PMID 10435631.
  3. Ling, L; Goeddel D V (August 2000). “T6BP, a TRAF6-interacting protein involved in IL-1 signaling”. Proc. Natl. Acad. Sci. U.S.A. UNITED STATES. 97 (17): 9567–72. Bibcode:2000PNAS…97.9567L. doi:10.1073/pnas.170279097. ISSN 0027-8424. PMC 16905. PMID 10920205.

Further reading



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