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TCH regimen

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:Docetaxel-Carboplatin-Trastuzumab Regimen; Taxotere-Carboplatin-Herceptin Regimen; TCH Regimen

Overview

TCH regimen refers to a sequential regimen consisting of multiple cycles of docetaxel (taxotere), carboplatin and trastuzumab (herceptin), followed by multiple cycles of trastuzumab alone, administered as a dose-dense regimen, and used in the adjuvant setting for the treatment of HER-2/neu-positive breast cancer.[1][2]

Regimen

TDocetaxel (Taxotere)

CCarboplatin

HTrastuzumab (Herceptin)

Indications

References

  1. 1.0 1.1 Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M; et al. (2011). “Adjuvant trastuzumab in HER2-positive breast cancer”. N Engl J Med. 365 (14): 1273–83. doi:10.1056/NEJMoa0910383. PMC 3268553. PMID 21991949.
  2. “NCI Thesaurus”.

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