Health Dictionary Find a Doctor

TNFAIP8

Tumor necrosis factor, alpha-induced protein 8 is a protein that in humans is encoded by the TNFAIP8 gene.[1][2][3] It is preferentially expressed in human immune cell types.[4]


References

  1. Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H (Jun 1999). “Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes”. Blood. 93 (10): 3418–31. PMID 10233894.
  2. Kumar D, Whiteside TL, Kasid U (Feb 2000). “Identification of a novel tumor necrosis factor-alpha-inducible gene, SCC-S2, containing the consensus sequence of a death effector domain of fas-associated death domain-like interleukin- 1beta-converting enzyme-inhibitory protein”. J Biol Chem. 275 (4): 2973–8. doi:10.1074/jbc.275.4.2973. PMID 10644768.
  3. “Entrez Gene: TNFAIP8 tumor necrosis factor, alpha-induced protein 8”.
  4. Li T, Wang W, et al. (May 2018). “Genome-wide analysis reveals TNFAIP8L2 as an immune checkpoint regulator of inflammation and metabolism”. Molecular Immunology. 99: 154–162. doi:10.1016/j.molimm.2018.05.007. PMID 29787979.

Further reading



© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH