Temporal arteritis risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]

Overview

Common risk factors in the development of temporal arteritis may be environmental, genetic, and viral. Common risk factors in the development of temporal arteritis include age, hypertension, and thrombocytosis. Less common risk factors in the development of temporal arteritis include allele HLA-DRB1*04 genetic polymorphisms, varicella zoster virus infection, and smoking.

The risk factors of temporal arteritis are as follows:

Common risk factors in the development of temporal arteritis may be environmental, genetic, and viral. Common risk factors in the development of temporal arteritis include:^[1]^[2]^[3]
- Age > 50 years
- Hypertension
- Thrombocytosis
- Female

Less common risk factors in the development of temporal arteritis include:^[4]
- Allele HLA-DRB1*04 genetic polymorphisms
- Varicella zoster virus infection
- Smoking

↑ Nesher G, Berkun Y, Mates M, Baras M, Nesher R, Rubinow A; et al. (2004). “Risk factors for cranial ischemic complications in giant cell arteritis”. Medicine (Baltimore). 83 (2): 114–22. PMID 15028965.
↑ González-Gay MA, García-Porrúa C, Llorca J, Hajeer AH, Brañas F, Dababneh A; et al. (2000). “Visual manifestations of giant cell arteritis. Trends and clinical spectrum in 161 patients”. Medicine (Baltimore). 79 (5): 283–92. PMID 11039076.
↑ Salvarani C, Cimino L, Macchioni P, Consonni D, Cantini F, Bajocchi G; et al. (2005). “Risk factors for visual loss in an Italian population-based cohort of patients with giant cell arteritis”. Arthritis Rheum. 53 (2): 293–7. doi:10.1002/art.21075. PMID 15818722.
↑ Mahr, A.; Aouba, A.; Richebé, P.; Gonzalez-Chiappe, S. (2017). “Épidémiologie et histoire naturelle de l’artérite à cellules géantes (Horton)”. La Revue de Médecine Interne. 38 (10): 663–669. doi:10.1016/j.revmed.2017.03.007. ISSN 0248-8663.