Thin basement membrane disease epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]

The incidence of thin basement membrane disease is 1%-2% based on data available in 2006. The prevalence of thin basement membrane disease is 1%.Thin basement membrane disease affects children and adult equally with more predominance in female. According to available data most cases are reported in developed countries specially in Europe where majority of patient are of Caucasians race. Chinese, Indians, Africans are less commonly affected.

• In 2006, the incidence of TBMD was estimated to be 1%-2% cases per 3471 TBMD cases on renal biopsy.^[1]

• The prevalence of TBMD is approximately 1%.^[2]

• There is no sufficient data available on case fatality rate or mortality rate.

• Patients of all age groups may develop Thin basement membrane disease. The median age of children is 7 years whereas in adult it is 37 years of age.^[3]

• Thin basement membrane disease usually affects individuals of the Caucasians according to available data. Chinese, Indians and African individuals are less likely to develop TBMD.

• Thin basement membrane diseaseaffects all ages of men and women equally.
• Some studies presented data showing women are more affected with TBMD than male.^[4]

• The majority of thin basement membrane disease cases are reported in Europe.

• The majority of TBMD cases are reported in Developed countries.

• There are no distinctive data showing the association of thin basement membrane disease with developing countries.

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