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Toxic Adenoma epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overveiw

The prevalence rates of toxic adenoma is 5-7% and 1-2% of all hyperthyroidism cases in women and men respectively. Toxic adenoma is more commonly seen in patients over 60 years. Similar to any thyroid disease females are more commonly affected by toxic adenoma than males. The female-to-male ratio is 5.9:1 for toxic adenoma.

Epidemiology

Prevalance

  • Toxic adenoma prevalence is inversely related to a population’s dietary iodine sufficiency.
  • In women and men, the prevalence rate of toxic adenoma is 5-7% and 1-2%, respectively.

Demographics

Age

  • The incidence of toxic adenoma increases with age; the median age at diagnosis is 50 years.[1]
  • Toxic adenoma is more commonly seen in patients over 60 years.

Race

There is no racial predilection to toxic adenoma.

Gender

  • Similar to any thyroid disease females are more commonly affected by toxic adenoma than males.
  • In women and men, the prevalence rate of palpable nodules is 5-7% and 1-2%, respectively.
  • The female-to-male ratio is 5.9:1 for toxic adenoma.

References

  1. Hamburger JI (1980). “Evolution of toxicity in solitary nontoxic autonomously functioning thyroid nodules”. J. Clin. Endocrinol. Metab. 50 (6): 1089–93. doi:10.1210/jcem-50-6-1089. PMID 7372787.

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