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Transient erythroblastopenia of childhood

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood characterized by gradual onset of pallor.

Historical Perspective

Classification

Pathophysiology

Causes

The cause of TEC is unknown, but it has been suggested that an infection with Parvovirus B19 plays a role.

Differentiating Transient erythroblastopenia of childhood from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

Most patients recover completely within 1-2 months.

Diagnosis

Diagnostic Criteria

History and Symptoms

Individuals with TEC have a median age of presentation of 18-26 months; however, the disorder may occur in infants younger than 6 months and in children as old as age 10 years. Because of the gradual onset of the anemia, children are often healthier than expected from their low hemoglobin levels.

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

References

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