Transient hypogammaglobulinemia of infancy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Transient hypogammaglobulinemia of infancy is a form of hypogammaglobulinemia appearing after birth, leading to a reduction in the level of IgG, and also sometimes IgA[1] and IgM.[2] (The ratios of immunoglobulins vary rapidly in all infants, and the term dysgammaglobulinemia, although theoretically applicable, isn’t usually used in this context.)
It can result in increased infections, but it can also present without symptoms.[3]
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Transient hypogammaglobulinemia of infancy from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
- ↑ “Transient Hypogammaglobulinemia of Infancy: Immunodeficiency Disorders: Merck Manual Professional”. Retrieved 2008-03-01.
- ↑ Kiliç SS, Tezcan I, Sanal O, Metin A, Ersoy F (2000). “Transient hypogammaglobulinemia of infancy: clinical and immunologic features of 40 new cases”. Pediatr Int. 42 (6): 647–50. PMID 11192522.
- ↑ Hsueh KC, Chiu HH, Lin HC, Hsu CH, Tsai FJ (2005). “Transient hypogammaglobulinemia of infancy presenting as Staphylococcus aureus sepsis with deep neck infection”. J Microbiol Immunol Infect. 38 (2): 141–4. PMID 15843860.
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