Transmissible spongiform encephalopathy history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Symptoms

The clinical symptoms in humans vary, but commonly include personality changes, psychiatric problems such as depression, lack of coordination, and/or an unsteady gait (ataxia). Patients also may experience involuntary jerking movements called myoclonus, unusual sensations, insomnia, confusion, or memory problems. In the later stages of the disease, patients have severe mental impairment (dementia) and lose the ability to move or speak.^[1]

References

↑ Collinge J (2001). “Prion diseases of humans and animals: their causes and molecular basis”. Annu Rev Neurosci. 24: 519–50. PMID 11283320.

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[1] Collinge J (2001). “Prion diseases of humans and animals: their causes and molecular basis”. Annu Rev Neurosci. 24: 519–50. PMID 11283320.

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