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Traumatic brain injury future or investigational therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Joanna Ekabua, M.D. [2]

Overview

In spite of robust experiments on the efficacy of neuroprotective drugs tested in animal models of traumatic brain injury, all Phase III clinical trials of neuroprotection have failed in patients with traumatic brain injury.

Future Or Investigational Therapies

In spite of robust experiments on the efficacy of neuroprotective drugs tested in animal models of traumatic brain injury, all Phase III clinical trials of neuroprotection have failed in patients with traumatic brain injury.[1][2]

References

  1. Xiong Y, Mahmood A, Chopp M (2009). “Emerging treatments for traumatic brain injury”. Expert Opin Emerg Drugs. 14 (1): 67–84. doi:10.1517/14728210902769601. PMC 2773142. PMID 19249984.
  2. Xiong Y, Zhang Y, Mahmood A, Chopp M (2015). “Investigational agents for treatment of traumatic brain injury”. Expert Opin Investig Drugs. 24 (6): 743–60. doi:10.1517/13543784.2015.1021919. PMC 4433440. PMID 25727893.


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