Tropical spastic paraparesis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Patients with HAM/TSP may exhibit uveitis (inflammation of the uveal tract of the eye), arthritis (inflammation of one or more joints), pulmonary lymphocytic alveolitis (inflammation of the lung tissues), polymyositis (an inflammatory muscle disease), keratoconjunctivitis sicca (persistent dryness of the cornea and conjunctiva), and infectious dermatitis (inflammation of the skin). Co-factors that may play a role in transmitting the disorder include being a recipient of transfusion blood products (especially before 1989), breastmilk feeding from a seropositive mother, intravenous drug use, or being the sexual partner of a seropositive individual for several years.

• Progressive muscle weakness;
• Sensory disturbance
• Sphincter dysfunction
• Urinary incontinence
• Uveitis
• Arthritis
• Pulmonary lymphocyte alveolitis
• Polymyositis
• Keratoconjunctivitis sicca
• Infectious dermatitis

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