Tumor lysis syndrome physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Nazia Fuad M.D.

Overview

Common physical examination findings of tumor lysis syndrome include fever, tachycardia, edema, cardiac arrhythmia, and tetany.

Physical Examination

Common physical examination findings of tumor lysis syndrome include:^[1]

Appearance of the patient

The general appearance of the patient depends on the severity and the cause of tumor lysis syndrome. The patient may be confused, and may appear anxious and may have difficulty breathing.

Vital signs

Skin

Lungs

Rales
Dyspnea
Distant breath sounds
Bronchospasm

Abdomen

Flank tenderness
Distention

Extremities

Tetany
Edema
Carpal spasm
Pedal spasm

Eye

Iritis

Neurologic

Altered mental status
Confusion
Delirium
Seizures
Paresthesia

References

↑ Cairo MS, Bishop M (2004). “Tumour lysis syndrome: new therapeutic strategies and classification”. Br J Haematol. 127 (1): 3–11. doi:10.1111/j.1365-2141.2004.05094.x. PMID 15384972.

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[pmid15384972-1] Cairo MS, Bishop M (2004). “Tumour lysis syndrome: new therapeutic strategies and classification”. Br J Haematol. 127 (1): 3–11. doi:10.1111/j.1365-2141.2004.05094.x. PMID 15384972.

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