Urorectal septum

Overview

The entodermal cloaca is divided into a dorsal and a ventral part by means of a partition, the urorectal septum, which grows downward from the ridge separating the allantoic from the cloacal opening of the intestine and ultimately fuses with the cloacal membrane and divides it into an anal and a urogenital part. The dorsal part of the cloaca forms the rectum, and the anterior part of the urogenital sinus and bladder.

Clinical significance

Malformation of the urorectal septum can lead to several different types of fistulas.^[1]

References

↑ Escobar LF, Heiman M, Zimmer D, Careskey H (2007). “Urorectal septum malformation sequence: Prenatal progression, clinical report, and embryology review”. Am. J. Med. Genet. A. 143 (22): 2722–6. doi:10.1002/ajmg.a.31925. PMID 17937427.

External links

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[pmid17937427-1] Escobar LF, Heiman M, Zimmer D, Careskey H (2007). “Urorectal septum malformation sequence: Prenatal progression, clinical report, and embryology review”. Am. J. Med. Genet. A. 143 (22): 2722–6. doi:10.1002/ajmg.a.31925. PMID 17937427.

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