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Uveitis differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Overview

Uveitis must be differentiated from other diseases that cause conjunctival injection, eye pain, photophobia, or visual disturbance. Masquerade syndromes, which are ophthalmic disorders that clinically present as either an anterior or posterior uveitis but are not primarily inflammatory, must be differentiated from uveitis. As uveitis manifests in a variety of clinical etiologies, differentiation must also be established in accordance with the particular subtype.[1][2][3][4]

Differential Diagnosis

Uveitis must be differentiated from other diseases that cause conjunctival injection, eye pain, photophobia, or visual disturbance. Masquerade syndromes, which are ophthalmic disorders that clinically present as either an anterior or posterior uveitis but are not primarily inflammatory, must be differentiated from uveitis. As uveitis manifests in a variety of clinical etiologies, differentiation must also be established in accordance with the particular subtype.[1][2][3][4]

Differentiating Uveitis from Other Diseases

Uveitis must be differentiated from other diseases that cause conjunctival injection, eye pain, photophobia, or visual disturbance, and include:[5][6][7]

Masquerade syndromes

Masquerade syndromes are ophthalmic disorders that clinically present as either an anterior or posterior uveitis, but are not primarily inflammatory. The following are some of the most common:[4]

  • Anterior segment
  • Posterior segment

References

  1. ↑ 1.0 1.1 Prior-Español Á, Martínez-Morillo M, Holgado-Pérez S, Juega FJ (2016). “Differential diagnosis of acute bilateral uveitis in the rheumatologist’s office”. Reumatol Clin. 12 (3): 174–175. doi:10.1016/j.reuma.2015.05.012. PMID 26187650.
  2. ↑ 2.0 2.1 Guly CM, Forrester JV (2010). “Investigation and management of uveitis”. BMJ. 341: c4976. doi:10.1136/bmj.c4976. PMID 20943722.
  3. ↑ 3.0 3.1 American Academy of Ophthalmology EyeWiki (2015)http://eyewiki.aao.org/Category:Uveitis
  4. ↑ 4.0 4.1 4.2 Rothova A, Ooijman F, Kerkhoff F, Van Der Lelij A, Lokhorst HM (2001). “Uveitis masquerade syndromes”. Ophthalmology. 108 (2): 386–99. PMID 11158819.
  5. ↑ Dart JK (1986). “Eye disease at a community health centre”. Br Med J (Clin Res Ed). 293 (6560): 1477–80. PMC 1342247. PMID 3099921.
  6. ↑ Leibowitz HM (2000). “The red eye”. N Engl J Med. 343 (5): 345–51. doi:10.1056/NEJM200008033430507. PMID 10922425.
  7. ↑ University of Michigan Eyes Have it (2009)http://kellogg.umich.edu/theeyeshaveit/red-eye/

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