VIPoma epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]Parminder Dhingra, M.D. [3] Homa Najafi, M.D.[4]

The annual incidence of VIPoma is approximately 0.01 per 100,000 (approx. 1 in 10 million) individuals worldwide. Female are more commonly affected by VIPoma than male. The incidence of VIPoma increases with age, the median age at diagnosis in adults is 50 years. VIPoma in children is usually diagnosed between age 2 to 4.

• The annual incidence of VIPoma is approximately 0.01 per 100,000 (approx. 1 in 10 million) individuals worldwide .^[1]

• Female are more commonly affected by VIPoma than male. The female to male ratio is approximately 3 to 1 in adults. ^[1]

• The incidence of VIPoma increases with age, the median age at diagnosis in adults is 50 years.^[1][2][3]
• VIPoma in children is usually diagnosed between age 2 to 4.
• VIPoma in children though uncommon, is usually ganglioneuromas or ganglioneuroblastomas which develop from neural crest tissue of sympathetic ganglia or adrenal medulla.

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