VIPoma historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]Parminder Dhingra, M.D. [3] Homa Najafi, M.D.[4]

Overview

VIPoma which is also known as Verner-Morrison syndrome was first described in 1958 by Verner and Morrison.

In 1870, Rudolf Heidenhain was the first to discover and describe the neuroendocrine tumors of the gastrointestinal tract and pancreas.
In 1958, American physicians, John U. Verner and Ashton B. Morrison discovered VIPoma for the first time in a patient presenting with profuse diarrhea and hypokalemia.
John U. Verner and Ashton B also described the pathogenesis of VIPoma (due to malignancy of non-insulin producing pancreatic islets) in detail.
VIPoma is also known as Verner-Morrison syndrome.^[1]

↑ Belei OA, Heredea ER, Boeriu E, Marcovici TM, Cerbu S, Mărginean O; et al. (2017). “Verner-Morrison syndrome. Literature review”. Rom J Morphol Embryol. 58 (2): 371–376. PMID 28730220.