Valaciclovir overdose

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Caution should be exercised to prevent inadvertent overdose. Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored

Adapted from the FDA Package Insert.