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Von Willebrand disease screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]

Overview

The ISTH-Bleeding Assessment Tool is a validated instrument that is used to screen patients referred for bleeding symptoms for further laboratory testing. The three main screening tests used in the diagnosis of VWD include vonWillebrand Factor (VWF) antigen, platelet-dependent VWF activity, and factor VIII activity.

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Screening

The ISTH-Bleeding Assessment Tool is a validated instrument that is used to screen patients referred for bleeding symptoms for further laboratory testing.[1]

The three main screening tests used in the diagnosis of VWD include:

  • VonWillebrand Factor (VWF) antigen
  • Platelet-dependent VWF activity
  • Factor VIII activity.

References

  1. Rao ES, Ng CJ (July 2018). “Current approaches to diagnostic testing in von Willebrand Disease”. Transfus. Apher. Sci. doi:10.1016/j.transci.2018.07.005. PMID 30064913.

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