Vulvar cancer history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2] Syed Musadiq Ali M.B.B.S.[3]

Overview

Symptoms of vulvar cancer include vulvar ulcers, lumps, discoloration, thickening of skin, pain or discomfort in the vulva and chronic pruritis of the vulva.

History and Symptoms

History

Vulvar cancer is a long history of pruritus. Less common presenting symptoms include vulvar bleeding, discharge, dysuria, and pain. The most common presenting sign of vulvar cancer is a vulvar lump or mass. Rarely, patients present with a large, fungating mass^[1].

Symptoms

Vulvar cancer may cause symptoms in its early stages.^[2]^[3]^[4]^[5]

Early symptoms

Vulvar ulcers
Chronic pruritus of the vulva
Pink, red, white, or any other discoloration of the vulva
Scaly or wart-like patches on vulva
Thickened skin
Pain or discomfort in the vulva
Changes in the appearance of a mole on the vulva (it may become larger or change color or shape)
Lump on the vulva

Late symptoms

Severe pruritus
Large lump on the vulva
Dysuria
Dyspareunia
Unusual bleeding or discharge from the lesion
Inguinal nodes

References

↑ Bigby SM, Eva LJ, Fong KL, Jones RW (November 2016). “The Natural History of Vulvar Intraepithelial Neoplasia, Differentiated Type: Evidence for Progression and Diagnostic Challenges”. Int. J. Gynecol. Pathol. 35 (6): 574–584. doi:10.1097/PGP.0000000000000280. PMID 26974999.
↑ Signs and symptoms of vulvar cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/vulvar/signs-and-symptoms/?region=nAccessed on September 26, 2015
↑ Zacur H, Genadry R, Woodruff JD (April 1980). “The patient-at-risk for development of vulvar cancer”. Gynecol. Oncol. 9 (2): 199–208. PMID 7372192.
↑ Collins CG, Lee FY, Roman-Lopez JJ (February 1971). “Invasive carcinoma of the vulva with lymph node metastasis”. Am. J. Obstet. Gynecol. 109 (3): 446–52. PMID 5549186.
↑ Alkatout I, Schubert M, Garbrecht N, Weigel MT, Jonat W, Mundhenke C, Günther V (2015). “Vulvar cancer: epidemiology, clinical presentation, and management options”. Int J Womens Health. 7: 305–13. doi:10.2147/IJWH.S68979. PMC 4374790. PMID 25848321.

[pmid26974999-1] Bigby SM, Eva LJ, Fong KL, Jones RW (November 2016). “The Natural History of Vulvar Intraepithelial Neoplasia, Differentiated Type: Evidence for Progression and Diagnostic Challenges”. Int. J. Gynecol. Pathol. 35 (6): 574–584. doi:10.1097/PGP.0000000000000280. PMID 26974999.

[xyz-2] Signs and symptoms of vulvar cancer. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/vulvar/signs-and-symptoms/?region=nAccessed on September 26, 2015

[pmid7372192-3] Zacur H, Genadry R, Woodruff JD (April 1980). “The patient-at-risk for development of vulvar cancer”. Gynecol. Oncol. 9 (2): 199–208. PMID 7372192.

[pmid5549186-4] Collins CG, Lee FY, Roman-Lopez JJ (February 1971). “Invasive carcinoma of the vulva with lymph node metastasis”. Am. J. Obstet. Gynecol. 109 (3): 446–52. PMID 5549186.

[pmid25848321-5] Alkatout I, Schubert M, Garbrecht N, Weigel MT, Jonat W, Mundhenke C, Günther V (2015). “Vulvar cancer: epidemiology, clinical presentation, and management options”. Int J Womens Health. 7: 305–13. doi:10.2147/IJWH.S68979. PMC 4374790. PMID 25848321.

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