Wilms' tumor historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]

Overview

Wilms Tumor was first discovered by Dr. Osler, in 1814.The association between tumor 1 gene (WT1) and Wilms tumor was made in 1990. Wilms tumor is named after Dr. Max Wilms (1867-1918) who is a surgeon and pathologist from Germany. In 1969, the National Wilms Tumor Study (NWTS) group devised a therapy regimen for Wilms tumor.

Historical Perspective

Wilms Tumor was first discovered by Dr. Osler, in 1814.
The association between Wilms tumor 1 (WT1) gene and Wilms tumor was made in 1990.^[1]
Wilms tumor is named after Dr. Max Wilms (1867-1918) who was a surgeon and pathologist from Germany.^[2]
In 1969, the National Wilms Tumor Study (NWTS) Group devised a therapy regimen for Wilms tumor.^[3]

References

↑ Ariza L, Cañete A, Rojas A, Muñoz-Chápuli R, Carmona R (April 2018). “Role of the Wilms’ tumor suppressor gene Wt1 in pancreatic development”. Dev. Dyn. doi:10.1002/dvdy.24636. PMID 29708625.
↑ Raffensperger J (February 2015). “Max Wilms and his tumor”. J. Pediatr. Surg. 50 (2): 356–9. doi:10.1016/j.jpedsurg.2014.10.054. PMID 25638637.
↑ Davidoff, Andrew M. (2012). “Wilms Tumor”. Advances in Pediatrics. 59 (1): 247–267. doi:10.1016/j.yapd.2012.04.001. ISSN 0065-3101.

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[pmid29708625-1] Ariza L, Cañete A, Rojas A, Muñoz-Chápuli R, Carmona R (April 2018). “Role of the Wilms’ tumor suppressor gene Wt1 in pancreatic development”. Dev. Dyn. doi:10.1002/dvdy.24636. PMID 29708625.

[pmid256386372-2] Raffensperger J (February 2015). “Max Wilms and his tumor”. J. Pediatr. Surg. 50 (2): 356–9. doi:10.1016/j.jpedsurg.2014.10.054. PMID 25638637.

[Davidoff2012-3] Davidoff, Andrew M. (2012). “Wilms Tumor”. Advances in Pediatrics. 59 (1): 247–267. doi:10.1016/j.yapd.2012.04.001. ISSN 0065-3101.

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