Wilms' tumor laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]

The lab studies conducted in patients suspected with Wilms tumor are Complete blood count (CBC), coagulation studies, Urinalysis, liver function test, serum creatinine, serum calcium and Cytogenetics studies.

• The following lab studies are conducted in patients suspected with Wilms tumor:
  • Complete blood count (CBC)
  • Coagulation studies
    • von Willebrand assay
      • Should be performed in children with history of vascular diseases or bleeding.
      • Acquired Von Willebrand’s disease can be present in patients suffering from Wilms tumor.^[1]
      • This is done as a precaution to risk of bleeding that can occur in case of interventions done for Wilms tumor.
  • Urinalysis
  • Liver function test
    • Abnormal in case of liver metastasis of Wilms tumor.
  • Serum creatinine
    • Should be performed before and after surgical intervention.
  • Serum calcium^[2]
    • May be elevated in children suffering from rhabdoid tumor of kidney.
    • May be elevated in children suffering from congenital mesoblastic nephroma.
  • Cytogenetics studies

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