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Wilson's disease surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Surgery is not the first-line treatment option for patients with Wilson’s disease. Surgery is usually reserved for patients with acute hepatitis and unresponsive to the medical therapy. Liver transplantation is recommended in patients with acute liver failure.

Surgery

  • Surgery is not the first-line treatment option for patients with Wilson’s disease. Surgery is usually reserved for patients with acute hepatitis and patients unresponsive to the medical therapy.[1]
  • Liver transplantation is the surgical option for the patients with Wilson’s disease and have acute liver failure. Liver transplant may be curative against Wilson’s disease and has shown good outcome in patients with acute liver failure.[2][3]

References

  1. Bellary S, Hassanein T, Van Thiel DH (1995). “Liver transplantation for Wilson’s disease”. J Hepatol. 23 (4): 373–81. PMID 8655953.
  2. “www.aasld.org” (PDF).
  3. European Association for Study of Liver (2012). “EASL Clinical Practice Guidelines: Wilson’s disease”. J Hepatol. 56 (3): 671–85. doi:10.1016/j.jhep.2011.11.007. PMID 22340672.

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