Yersinia pestis infection future or investigational therapies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Current research aims to develop new and less invasive vaccines that protect from airborne infection of Yersinia pestis.
Future and Investigational Therapies
Research studies are under way to improve the plague vaccine. The qualities searched in the new vaccine include:[1]
- Protection from airborne infection
- Inhaled administration
A current potential vaccine is a recombinant type, expressing both V and F1 antigens of Yersinia pestis. This vaccine appears to protect animals against airborne infection with Yersinia pestis. Other options include:[1]
- Aerosolized monoclonal antibodies
- Attenuated form of Yersinia pseudotuberculosis
References
- ↑ 1.0 1.1 Mandell, Gerald (2010). Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Philadelphia, PA: Churchill Livingstone/Elsevier. ISBN 0443068399.
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