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ZC3H12A

Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.[1]

ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.

References

Further reading

  • Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE, Fu M (2008). “A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages”. The Journal of Biological Chemistry. 283 (10): 6337–46. doi:10.1074/jbc.M707861200. PMID 18178554.


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