Zygomycosis surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Surgical therapy can be very drastic for zygomycosis, and in some cases of Rhinocerebral disease removal of infected brain tissue may be required. In some cases surgery may be disfiguring because it may involve removal of the palate, nasal cavity, or eye structures. Surgery may be extended to more than one operation. It has been hypothesised that hyperbaric oxygen may be beneficial as an adjunctive therapy because higher oxygen pressure increases the ability of neutrophils to kill the organism.

Treatment for Phycomycosis is very difficult and includes surgery when possible. Postoperative recurrence is common. For pythiosis and lagenidiosis, a new drug targeting water moulds called caspofungin is available, but it is very expensive.

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