17 alpha-hydroxylase deficiency prevention

Prenatal diagnosis of 17 alpha-hydroxylase deficiency is advised in order to prevent complications of the disease further in life. Prenatal administration of dexamethasone, which is the drug of choice helps prevent complications.

• Prenatal diagnosis of 17 alpha-hydroxylase deficiency is advised in order to prevent complications of the disease further in life.
• Prenatal administration of dexamethasone, which is the drug of choice helps prevent complications. 
• Testing modalities include:
  • Amniotic fluid testing.
  • Oligonucleotide hybridization of deoxyribonucleic acid (DNA) which is obtained from chorionic villus biopsies. In this method, fetal DNA is extracted from maternal blood through noninvasive methods.^[1]