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2-bromopropane
Introduction
Overview
Overview
2-Bromopropane, also known as isopropyl bromide is the halogenated hydrocarbon with the formula CH3CHBrCH3. It is a colorless liquid. It is used for introducing the isopropyl functional group in organic synthesis.
Reactions
Reactions
The bromine atom is at the secondary position, which allows the molecule to undergo dehydrohalogenation easily to give propene, which escapes as a gas. Consequently, this reagent is used in conjunction with mild bases such as potassium carbonate, vs strong ones.
Safety
Safety
Alkylating agents are often carcinogenic.
Further reading
Further reading
- M G. Gergel “Excuse Me Sir, Would You Like to Buy a Kilo of Isopropyl Bromide?” Pierce Chemical Co. (1979). (story of start-up chemical company).