Health Dictionary Find a Doctor

21-hydroxylase deficiency secondary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]

Overview

Overview

Continued monitoring of hormone balance and careful readjustment of glucocorticoid dose is helpful in controlling fertility and preventing adrenal crisis in patient with 21-hydroxylase deficiency.

Secondary Prevention

Secondary Prevention

Preventing hyperandrogenism and optimizing fertility

Continued monitoring of hormone balance and careful adjustment of glucocorticoid dose is helpful in controlling infertility. In general, women with 21-hydroxylase deficiency have a lower fertility rate.[1]

Preventing adrenal crisis

To prevent adrenal crisis, all patients taking glucocorticoids replacement should take bolus dose of glucocorticoids during severe illness, surgery and severe exhaustion.

References

References

  1. Mnif MF, Kamoun M, Kacem FH, Mnif F, Charfi N, Naceur BB, Rekik N, Abid M (2013). “Reproductive outcomes of female patients with congenital adrenal hyperplasia due to 21-hydroxylase defi ciency”. Indian J Endocrinol Metab. 17 (5): 790–3. doi:10.4103/2230-8210.117196. PMC 3784860. PMID 24083158.

Template:WH Template:WS

Looking for the patient version?

Back to the patient-friendly article

© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH