Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
21-hydroxylase deficiency surgery
Introduction
Overview
Overview
Reconstructive surgery and surgical adrenalectomy are the surgical procedures used for patients with 21-hydroxylase deficiency. Reconstructive gynecologic surgery may be used in adolescents or adults, including clitoroplasty and vaginoplasty. Surgical adrenalectomy can be done in some cases, if there is no response to medical therapy.
Surgery
Surgery
Reconstructive surgery
- Reconstructive gynecologic surgery may be used in adolescents or adults, including clitoroplasty and vaginoplasty. [1]
Surgical adrenalectomy
- Surgical adrenalectomy can be done in some cases, if there is no response to medical therapy.
- The major benefit is lowering adrenal androgen and progesterone secretion. However, it increases dependency on glucocorticoid and mineralocorticoid replacement therapy. [2]
References
References
- ↑ Premawardhana LD, Hughes IA, Read GF, Scanlon MF (1997). “Longer term outcome in females with congenital adrenal hyperplasia (CAH): the Cardiff experience”. Clin Endocrinol (Oxf). 46 (3): 327–32. PMID 9156043.
- ↑ Crocker MK, Barak S, Millo CM, Beall SA, Niyyati M, Chang R; et al. (2012). “Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia”. J Clin Endocrinol Metab. 97 (11): E2084–9. doi:10.1210/jc.2012-2298. PMC 3485588. PMID 22904181.
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Â ;Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]