
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
4-dimethylaminophenol
Introduction
Overview
Overview
4-Dimethylaminophenol (abbreviated in medical practice as DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.
Uses
Uses
4-Dimethylaminophenol has been used as an antidote for cyanide poisoning.It has also been shown to be effective in treating hydrogen sulfide toxicity.
It works by generating methemoglobin.
This is suitable as an emergency treatment only; treatment must be followed up with sodium thiosulfate or cobalamin.
In an animal model, it has shown effectiveness when given intramuscularly.Though, intramuscular injection should be avoided due to the probability of muscular necrosis after injection. Intravenous injection is recommended in a dose of 250mg.
References
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
