
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Achalasia risk factors
Introduction
Overview
Overview
The most potent risk factor in the development of achalasia is Allgrove syndrome. Other risk factors include herpes infection, measles infection, autoimmune diseases, and HLA type 2.
Risk Factors
Risk Factors
- Allgrove syndrome, also known as triple-A syndrome (AAA), or as Achalasia-Addisonianism-Alacrimia syndrome[1][2][3][4]
- Herpes infection[1]
- Measles infection[2]
- Autoimmune diseases[3]
- HLA type 2[4]
References
References
- β 1.0 1.1 Castagliuolo I, Brun P, Costantini M, Rizzetto C, PalΓΉ G, Costantino M; et al. (2004). “Esophageal achalasia: is the herpes simplex virus really innocent?”. J Gastrointest Surg. 8 (1): 24β30, discussion 30. PMIDΒ 14746832.
- β 2.0 2.1 Jones DB, Mayberry JF, Rhodes J, Munro J (1983). “Preliminary report of an association between measles virus and achalasia”. J Clin Pathol. 36 (6): 655β7. PMCΒ 498344. PMIDΒ 6853731.
- β 3.0 3.1 Booy JD, Takata J, Tomlinson G, Urbach DR (2012). “The prevalence of autoimmune disease in patients with esophageal achalasia”. Dis Esophagus. 25 (3): 209β13. doi:10.1111/j.1442-2050.2011.01249.x. PMIDΒ 21899655.
- β 4.0 4.1 De la Concha EG, Fernandez-Arquero M, Mendoza JL, Conejero L, Figueredo MA, Perez de la Serna J; et al. (1998). “Contribution of HLA class II genes to susceptibility in achalasia”. Tissue Antigens. 52 (4): 381β4. PMIDΒ 9820602.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Rim Halaby, Ahmed Younes M.B.B.CH [2]
