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Actinomycosis laboratory tests
Introduction
Overview
Overview
The diagnosis of actinomycosis can be confirmed by either a positive bacterial culture or by histopathological identification.
Laboratory findings
Laboratory findings
The gold standard for diagnosing actinomycosis is the histological examination and bacterial culture. Other laboratory findings are non-specific and include[1][2]
CBC
- Anemia with mild leucocytosis
- Elevated ESR, and CRP
- Elevated alkaline phosphatase in hepatic actinomycosis
Culture
- The isolation and identification of Actinomyces can confirm a diagnosis of actinomycosis.
- Common clinical specimens employed in isolation are samples of pus from infected tissue.
- Cultures are positive between the 7th and 21st day when grown anaerobically at 37°C.
Histopathology
Findings on microscopy that are supportive for diagnosing actinomycosis include:
- Gram-positive
- Filamentous organisms
- Sulfur granules
Gallery
Gallery
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![Actinomycosis bovis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/f/f6/Actinomyces_bovis04.jpeg)
Actinomycosis bovis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis bovis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/7/76/Actinomyces_bovis05.jpeg)
Actinomycosis bovis. From Public Health Image Library (PHIL). [3] -
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/f/f6/Actinomyces_sp01.jpeg)
Actinomyces sp. From Public Health Image Library (PHIL). [3] -
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/9/9d/Actinomyces_sp02.jpeg)
Actinomyces sp. From Public Health Image Library (PHIL). [3] -
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/c/cb/Actinomyces_sp03.jpeg)
Actinomyces sp. From Public Health Image Library (PHIL). [3] -
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/5/52/Actinomyces_sp05.jpeg)
Actinomyces sp. From Public Health Image Library (PHIL). [3] -
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/7/7f/Actinomyces_sp06.jpeg)
Actinomyces sp. From Public Health Image Library (PHIL). [3] -
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/d/d4/Actinomyces_sp09.jpeg)
Actinomyces sp. From Public Health Image Library (PHIL). [3] -
![Actinomycosis viscosus. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/f/f7/Actinomyces_viscosus01.jpeg)
Actinomycosis viscosus. From Public Health Image Library (PHIL). [3] -
![Actinomycosis viscosus. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/1/1c/Actinomyces_viscosus02.jpeg)
Actinomycosis viscosus. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/4/4d/Actinomycosis01.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/8/82/Actinomycosis02.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/1/1b/Actinomycosis03.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/5/54/Actinomycosis04.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/9/96/Actinomycosis05.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/7/7e/Actinomycosis06.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/e/eb/Actinomycosis07.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/1/1e/Actinomycosis08.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/7/7f/Actinomycosis09.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/3/35/Actinomycosis10.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/d/d6/Actinomycosis11.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/f/fd/Actinomycosis12.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/0/09/Actinomycosis13.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/7/71/Actinomycosis14.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/1/13/Actinomycosis15.jpeg)
Actinomycosis. From Public Health Image Library (PHIL). [3] -
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/4/46/Actinomyces_naeslundi01.jpeg)
Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3] -
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/f/fa/Actinomyces_naeslundi04.jpeg)
Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3] -
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/e/e3/Actinomyces_naeslundi05.jpeg)
Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3] -
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/images/e/e1/Actinomyces_naeslundi03.jpeg)
Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]
![Actinomycosis bovis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_bovis04.jpeg)
![Actinomycosis bovis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_bovis05.jpeg)
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_sp01.jpeg)
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_sp02.jpeg)
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_sp03.jpeg)
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_sp05.jpeg)
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_sp06.jpeg)
![Actinomyces sp. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_sp09.jpeg)
![Actinomycosis viscosus. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_viscosus01.jpeg)
![Actinomycosis viscosus. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_viscosus02.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis01.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis02.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis03.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis04.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis05.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis06.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis07.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis08.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis09.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis10.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis11.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis12.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis13.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis14.jpeg)
![Actinomycosis. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomycosis15.jpeg)
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_naeslundi01.jpeg)
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_naeslundi04.jpeg)
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_naeslundi05.jpeg)
![Actinomycosis naeslundi. From Public Health Image Library (PHIL). [3]](https://www.wikidoc.org/index.php/File%3AActinomyces_naeslundi03.jpeg)
References
References
- ↑ Acevedo F, Baudrand R, Letelier LM, Gaete P (2008). “Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature”. Int. J. Infect. Dis. 12 (4): 358–62. doi:10.1016/j.ijid.2007.10.006. PMID 18164641.
- ↑ Mani RK, Mishra V, Singh PK, Pradhan D (2017). “Pulmonary actinomycosis: a clinical surprise!”. BMJ Case Rep. 2017. doi:10.1136/bcr-2016-218959. PMID 28130291.
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 3.23 3.24 3.25 3.26 3.27 3.28 “Public Health Image Library (PHIL)”.
de:Aktinomykose gl:Actinomicose hr:Aktinomikoza nl:Actinomycose sr:Актиномикоза fi:Aktinomykoosi uk:Актиномікоз
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]Aditya Ganti M.B.B.S. [3]